First in Class Drugs for Neurodegenerative and Rare Diseases
The invention relates to 1,2,3-triazoles of formula:useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.
The present invention relates to substituted 1,2,3-triazoles useful for the treatment of
ocular diseases, in particular those related to retinal degeneration such as retinitis
pigmentosa. The invention also relates to a subgroup of new substituted 1,2,3-triazoles.
Under evaluation at least till: 10th of February 2023