A wearable ultrasound apparatus is disclosed for use in connection with various biomedical applications, including musculoskeletal (“MSK”) imaging and analysis, In at least one embodiment, the apparatus provides at least one of an ultrasound module configured for obtaining an at least one ultrasound image of a portion of a user’s body on which the at least one ultrasound module is positioned (hereinafter referred to as the “target site” for simplicity purposes), a electrophysiological (“EP”) module configured for detecting bioelectric signals of the target site, and a near-infrared spectroscopy (“NIRS”) module configured for monitoring oxygenation status and/or biochemical measurements of the target site